Fmoc-N-Me-D-Phg-OH

Fmoc-N-Me-D-Phg-OH, also known as the Fmoc-protected derivative of N-methyl-D-phenylglycine, is a valuable compound in fields such as biochemistry, peptide synthesis, and drug discovery.

Peptide Synthesis and Solid-Phase Peptide Synthesis:
Fmoc-N-Me-D-Phg-OH plays a crucial role in solid-phase peptide synthesis. As an amino acid monomer in this process, it connects with other amino acids through its N-terminal Fmoc protecting group. The water-solubility of the Fmoc group allows coupling and deprotection steps to be carried out under mild conditions, facilitating the efficient synthesis of peptide chains.
Drug Discovery:
Fmoc-N-Me-D-Phg-OH can be used as a building block for synthesizing biologically active peptides and proteins. By combining it with other amino acids, peptides or proteins with specific sequences and functions can be synthesized, which may exhibit therapeutic potential, such as enzyme inhibitors, receptor antagonists, or immunomodulators.
Biochemical Research:
In biochemical research, Fmoc-N-Me-D-Phg-OH can be used to synthesize labeled peptides or proteins for studies such as protein-protein interactions, enzyme kinetics, and cellular localization. Its introduction into peptide chains allows for convenient tracking and detection of peptide or protein behavior and function.
Biological Probes and Diagnostic Agents:
Fmoc-N-Me-D-Phg-OH can also be utilized in the synthesis of biological probes and diagnostic agents. Due to its specific chemical structure and modifiability, it can be used to label biological molecules such as antibodies, enzymes, or nucleic acids for applications in disease diagnosis, biological imaging, or drug screening.