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1118767-16-0 tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu

1118767-16-0 tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu

Short Description:

Appearance White to off-white powder
MF C43H79N3O13
MW 846.1
Purity 98+


Product Detail

Transportation condition
Could be in normal temperature

Recommend shipping method
By air     By land      By sea

Storage condition:
Keep in dark place,Inert atmosphere,Room temperature

shelf life
About 2 years

Minimum Order Qty:
1kg (negotiation)

Certification: COA, melting point, SpecificRotation [α]D20                      

We will send any data you want. You can see the data before as reference.

For customized products, we send the newest data after they come out.

D-Lys(tfa)-NCA (2)

Synonyms

tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu

inner Packing

They are often used for packing powder. It depends on customers` requirement. Therefore, tell us your demanding before packing if you have special requests.

Inner packing 2
Inner packing 1
Inner packing 3

outer packing

1kg to 25kg The outer packing is hard. And it is difficult to cut and damage. It can protect your products perfectly.

Outer packing 3
Outer packing 2
Outer packing 1

Applications

Firstly, the side chain of semaglutide is specifically designed and functionalized, playing a pivotal role in its pharmaceutical applications. This side chain, attached to the 26th lysine residue of the peptide chain, not only enhances the stability of the semaglutide structure but also facilitates its interaction with specific biological molecules.

Secondly, the side chain comprises an 18-carbon fatty diacid chain, which is synthesized through the conjugation of glutamic acid, two molecules of 8-amino-3,6-dioxaoctanoic acid (AEEA), and octadecanedioic acid. This unique side chain structure increases semaglutide's affinity for albumin, reducing renal clearance and prolonging its half-life in the body. This prolonged activity enhances the therapeutic effect and durability of the drug.

Furthermore, the pegylation of the side chain enhances semaglutide's solubility and mobility, minimizing renal filtration and proteolytic degradation. This modification also reduces the pyrogenicity of the drug and protects it from immune system attack, improving drug delivery and retention at the target site.

related products

Fmoc-AEEA-OH Fmoc-AEEA-AEEA-OH H-Glu-OtBU Boc-Glu-Otbu(Osu)
Fmoc-L-Ser(tBu)-OH Fmoc-L-Lys-OH·HCl

Why Choose Us

1. About the MOQ: We can adjust it according to your requirement.
2. About the sample: The sample requires the sample fee, which can be freight to collect or you can pay to us in advance.
3. Mold workshop, can be customized according to the number of models.
4. We provide the best service. An experienced sales team is already working for you.
5. About the exchange: Please email or chat me at your convenience.


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